Piano and cello doing devastating things together. Shiro to Kuro no Alice is an otome visual novel on Vita with a soundtrack built on this white-world/black-world duality that actually pays off musically. "お茶会のための弦楽奏" is literally string music for a tea party and it sounds exactly that elegant, plucked strings and delicate phrasing.
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Then "黒ノ陰謀" flips everything sinister with minor key piano runs that feel genuinely unsettling. "ピアノとチェロによるレクイエム" is the emotional gut punch, just two instruments carrying all the weight. The waltz theme tying it all together.
If you play otome games and skip the music, this is the one that'll make you stop and actually listen.