Danny Baranowsky went absolutely feral on this score. The Binding of Isaac's original 2011 soundtrack turns a Flash game about crying on your enemies into something that hits way harder than it should. "Sacrificial" has this grimy, distorted bass loop that gets stuck in your head for days, and then "Divine Combat" throws in these almost choral synths that feel genuinely unsettling.
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"Enmity of the Dark Lord" goes full dark electronic worship music somehow. The way it shifts between lo-fi dread and bursts of frantic energy. Every room change keeps you on edge because you never know if the next track is going to be meditative or absolutely punishing.
If you ever ugly-cried in a basement run, this soundtrack is why.